Mizzou Give Direct

College of Veterinary Medicine

Goal: $20,210

$525 (2%) raised Need: $19,685

College of Veterinary Medicine

99 Lives Cat Initiative

Thank you for supporting the 99 Lives Cat Genome Sequencing!

New goals for 2023 - 2024 – Help us raise $21,000 for cat research!

The 99 Lives Cat Genome Sequencing Initiative is a project that will read the entire DNA sequence of your cat’s 38 chromosomes! This data is used to identify DNA mutations causing interesting traits, like different coat colors and ear and tail types, or health problems. Healthy cats can participate to define the normal DNA sequence of different cat breeds and populations from around the world. The DNA from many wild felids, such as lions, tigers, and cheetahs, are also included. The many successes of the project are described in scientific publications associated with the 99 Lives Cat Genome Project (See publication list under 99 Lives on the lab website: http://felinegenetics.missouri.edu/). We have found many disease mutations such as blindness in Persians and Bengal cats, but also interesting phenotypic traits, like the Lykoi – werewolf cats and the Ticked mutation for Abyssinians and other breeds.

The costs for WGS have drastically reduced and the University of Missouri has the computing facilities to help analyze your cat’s genome! The more cats in the 99 Lives database – the more success we will have with finding the DNA variant that causes health problems and interesting traits. Normal cats are important too. Please nominate a specific cat representing a breed for DNA sequencing (See breed list under 99 Lives on the lab website: http://felinegenetics.missouri.edu/). These cats can have interesting traits, health problems or be perfectly normal! Please submit DNA from your cat and support the genome sequencing of its DNA for the 99 Lives Project. You can dedicate your donation to a specific cat, breed, or project! Cheek (buccal) swab samples are always needed to help verify our discoveries – please continue to send in samples for cats this traits and health concerns.

Please see more on how to participate in cat research at this link.

Active projects include:

  • Ragdolls – absent uterine horn and kidney

  • Egyptian Maus – urate stones

  • Transylvanian cats – defining the Karpati coloration and pattern

  • Burmese – stretchy skin – Ehlers-Danlos Syndrome

  • Burmese – Feline oral-facial pain (FOP)

  • Siberians – hypertrophic cardiomyopathy (HCM)

  • All cats – every cat – new heritable traits and diseases

  • Amyloidosis (in collaboration with the University of Milan and others)

    • Abyssinians/Somalis and Siamese/Orientals


Cats Rule! – Thank you for your support!